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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2D All Species: 18.48
Human Site: S180 Identified Species: 33.89
UniProt: Q14814 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14814 NP_005911.1 521 55938 S180 L T D P R L L S P Q Q P A L Q
Chimpanzee Pan troglodytes XP_001165500 521 55889 S180 L T D P R L L S P Q Q P A L Q
Rhesus Macaque Macaca mulatta XP_001103222 500 53974 L178 T L T D S S M L S P P Q T T L
Dog Lupus familis XP_547534 525 56508 V180 S Y R L A S A V P A P N F A M
Cat Felis silvestris
Mouse Mus musculus Q63943 514 54974 S180 L T D P R L L S P Q Q P A L Q
Rat Rattus norvegicus O89038 507 54350 S180 L T D P R L L S P Q Q P A L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507540 505 54598 P180 A D T S M L S P P Q A T L H R
Chicken Gallus gallus Q9W6U8 499 53650 Q182 T T M L S P P Q T T L H R N V
Frog Xenopus laevis Q03413 498 54053 S180 L T D P R L L S P P Q P S L Q
Zebra Danio Brachydanio rerio NP_571392 529 57466 P180 T D P R L L S P Q Q P Q L Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S180 T N I S P R P S S S E T D S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310
Baker's Yeast Sacchar. cerevisiae Q12224 676 73465 R180 D G S E Q N K R H P E N A L P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 53.7 72.5 N.A. 96.1 94.4 N.A. 54.1 54.7 73.6 70.1 N.A. 28 N.A. N.A. N.A.
Protein Similarity: 100 99.8 63.9 75.8 N.A. 97.1 95.5 N.A. 64.8 64.3 82.5 78.2 N.A. 39.5 N.A. N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 100 100 N.A. 20 6.6 86.6 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 6.6 N.A. 100 100 N.A. 26.6 6.6 93.3 20 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.2 22.1 N.A.
Protein Similarity: N.A. N.A. N.A. 34.9 38.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 8 0 0 8 8 0 39 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 16 39 8 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 16 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 8 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 39 8 0 16 8 54 39 8 0 0 8 0 16 47 8 % L
% Met: 0 0 8 0 8 0 8 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 0 16 0 8 0 % N
% Pro: 0 0 8 39 8 8 16 16 54 24 24 39 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 8 8 47 39 16 0 8 39 % Q
% Arg: 0 0 8 8 39 8 0 8 0 0 0 0 8 0 16 % R
% Ser: 8 0 8 16 16 16 16 47 16 8 0 0 8 8 0 % S
% Thr: 31 47 16 0 0 0 0 0 8 8 0 16 8 8 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _